RESUME
Larry Lenard Lowe, Ph.D.
PERSONAL DATA
Date of Birth: June 3, 1950
Place of Birth:
Citizenship:
Home:
Home Phone: 864/882-5188
Professor, 2003 – Present, Department of Biology, Chemistry and Environmental Health Science,
EDUCATION
Ph.D.,
M.S.,
B.S.,
Summer Science Program, Harvard University, Cambridge, MA, 1969, 1970 and 1971, Biology,
Chemistry and Kidney Transplantation Research
Exchange Student, University of California at Santa Cruz, Santa Cruz, CA, 1970, Biology
Summer School, University of Southern Mississippi, Hattiesburg, MS, 1972, Medical Genetics
PROFESSIONAL
EXPERIENCE
United States Department of State, January 2008 – January 2009, Science Advisor, Office of Defense Trade Controls Policy, Bureau of Political-Military Affairs,
William C. Foster Visiting Scholar, Washington, D.C.
Benedict College, 2003 - 2008, Chair, Department of Biology, Chemistry and Environmental Health Science, Columbia, SC
Benedict College, 2003 – 2004
Senior Principal Investigator (Mentor), 2003 – 2004, SC EPSCoR/IdeA Collaborative Research Project on “Aging Skeletal Muscle’s Decreased Regenerative Capacity”.
Larry Lowe (Benedict College) and James Carson (USC, Columbia Campus)
Benedict College, 1991 – 2002, Associate Professor of Biology, Department of Biological and Physical Science, Columbia, SC
Alcorn State University, 1988 – 1989, Associate Professor of Biology, Department of Biology, Lorman, MS
Atlanta University Center (Science Research Institute) and Morehouse School of Medicine, 1985 – 1988, Research Associate, Biology and Biochemistry,
Atlanta, GA
Emory University School of Medicine, 1982 – 1985, NIH Postdoctoral Fellow, Molecular Virology, Department of Microbiology and Immunology,
Atlanta, GA
Atlanta University, Morehouse College, Spellman College, 1980 – 1982, Instructor, Biology, Atlanta, GA
United States Centers for Disease Control, 1978 – 1980, Lab Bench Trainee, Molecular Virology, Nucleic Acid and Protein Chemistry, Atlanta, GA
CONSULTING
EXPERIENCE
University of South Carolina, Columbia, SC, Department of Mechanical Engineering, “Continuous Renewal of Undergraduate Education via an Interdisciplinary,
Inquiry-Based Laboratory” (2006 to present).
Allen University, Columbia, SC, NSF Science, Technology, Engineering and Mathematics Project, develop evaluation strategies for NSF Planning Grant (2002).
Benedict College Child Development Center, Columbia, SC, Science Curriculum Consultant, develop hands-on science activities for pre-school grade levels
(1995 to present).
Southern University, Baton Rouge, LA, Louisiana Alliance for Minority Participation (LAMP) MainSTey Project, develop TI-83 Calculator-Based Lab Science
and Math Handbook (published) (1996 – 1997).
Mississippi Institute of Higher Education, Jackson, MS, High School Teachers Enrichment Program in Genetics, taught statewide course in genetics including
innovative lab exercises to select High School Science Teachers in Mississippi (1988 -1989).
MEMBERSHIPS
Member, Association of Southeastern Biologist (2005 to present)
Member, NASA Astrobiology Institute’s Minority Astrobiology Institutions Collaborative (MIAC), (2001 to present)
Member, South Carolina Space Grant Consortium (1995 to present)
Member, South Carolina Academy of Science (1995 to present)
Member, Beta Kappa Chi National Scientific Honor Society (1978 to present)
Member, Outstanding Young Men of
Member, Phi Eta Sigma National Scientific Honor Society (1985)
Member, Sigma Xi, Scientific Research Society (1994)
PROFESSIONAL
ACTIVITIES
South Carolina Space Grant Consortium, Board of Directors, Research Advisory and Awards Committee(s) and Benedict College Campus Director
(1995 to present).
South Carolina Department of Education, Richland County School District I, PACT External Review Team Chair (2001).
Beta Kappa Chi National Scientific Honor Society, Chapter (Alpha Theta) Sponsor (1995 to present).
PUBLICATIONS
Kuner, S.,
Education, 17: No. 1, 2006.
McClung, JM, Mehl, KA, Thompson, RW, Lowe, LL, and Carson, JA. “Nandrolone Decanoate modulates cell cycle regulation in functionally
overloaded rat soleus muscle”. Am. J. Physiol. Integ. Comp. Physiol., 288: (2005).
J.M. McClung, R.W. Thompson, Larry L. Lowe, and J.A. Carson. “RhoA Expression During Recovery From Skeletal Muscle Disuse”.
Journal of Applied Physiology. 96: 1341 – 1348 (2004).
Tyrone A. Washington, James M. Reecy, Raymond W. Thompson, Larry L. Lowe, Joseph M. McClung, and James A. Carson. “Lactate
Dehydrogenase Expression at the Onset of Altered Loading in Rat Soleus Muscle.” Journal of Applied Physiology, 97: 1424 – 1430 (2004).
Washington, T.A., R.W. Thompson, L.L. Lowe, J.M. McClung and J.A. Carson, “Lactate Dehydrogenase Expression at the Onset of Altered Loading
in the Rat Soleus Muscle”. Medicine and Science in Sports and Exercise, 35(5): S206, (2003).
Joseph M. McClung, Won J. Lee, Raymond W. Thompson, Larry L. Lowe* and James A. Carson. “RhoA Induction by Functional Overload and
Nandrolone Decanoate Administration in Rat Skeletal Muscle”. European Journal of Physiology, 447(3): 345 – 355 (2003).
Guang jer Wu, Shu – Ying Lu, Larry L. Lowe and Joseph M. Kinkade, Jr., “Identification of Lactate Dehydrogenase-M Polypeptide Translated in
vitro from Human and Mouse tumor Cell Poly (A)-Containing mRNA”. International Journal of Biochemistry. Vol. 17: 133 – 137 (1985).
Conference Proceedings
(Reviewed)
Frassica, Michael1; Voglewede, Philip1; Esmaiel Jabbari2; Jed Lyons1; Annette Golonka3; Larry Lowe4, “Continuous Renewal of Undergraduate
Education via an
Interdisciplinary, Inquiry Based Bioengineering Laboratory”, Abstract, South Carolina Bioengineering Summit, June 2007.
1Department of Mechanical Engineering, University of South Carolina, Columbia, SC, 2Department of Chemical Engineering, University
of South Carolina, Columbia, SC, 3Biology, University of South Carolina – Lancaster, Lancaster, SC, 4Department of Biology, Chemistry and
Environmental Health Science, Benedict College, Columbia, SC.
Moore, A. and L. L. Lowe, “The Effects of
Microgravity Responsive cDNAs on the Phenotypic Expression of E. Coli Cells”, Abstract, 63rd Joint
Annual Meeting of Beta Kappa
Chi/National Institutes of Science/Brookhaven Semester Program, Montgomery,
Alabama (2006).
Bain, N. and L. L.
Lowe, “Immunological Characterization of Lactate Dehydrogenase in Adult Male Rat Skeletal Muscle Exposed to
Simulated
Microgravity”, Abstract, 63rd Joint Annual Meeting of Beta Kappa
Chi/National Institutes of Science/Brookhaven Semester Program,
Montgomery,
Alabama (2006).
Owens, W. and L. L. Lowe, “The Effects of
Microgravity on Skeletal Muscle Gene Expression”, Abstract,
63rd Joint Annual Meeting of Beta Kappa
Chi/National Institutes of
Science/Brookhaven Semester Program, Montgomery, Alabama (2006).
Washington, T. A., R.W. Thompson, L.L. Lowe, J.M.
McClung and J.A. Carson, “The Effects of Muscle Remodeling on Lactate
Dehydrogenase
Expression at the Onset of Altered
Loading in the Rat Soleus Muscle,” Abstract,
Southeastern American College of Sports Medicine,
Atlanta, GA, (2003).
Washington, T. A., J.M. McClung, L.L. Lowe, and
J.A. Carson, “Lactate Dehydrogenase
Activity in Functionally Overloaded Rat Plantaris Muscle”,
Abstract, Southeastern American College of Sports
Medicine National Meeting, St. Louis,
Washington, T. A., J.M. McClung, L.L. Lowe, and
J.A. Carson, “Decreased Lactate Dehydrogenase Activity in Functionally
Overloaded Rat Plantaris
Muscle”, Abstract, Southeastern American College of Sports Medicine
National Meeting, St. Louis,
Washington, T. A., J.M. McClung, L.L. Lowe, and
J.A. Carson, “Lactate Dehydrogenase
Activity in Functionally Overloaded Rat Plantaris
Muscle”, Abstract, Southeastern American College of Sports Medicine
National Meeting, Atlanta, GA, (2002).
Fast-Type Skeletal Muscle”, Abstract, Southeastern American
College of Sports Medicine National Meeting, Atlanta, GA, (2002).
National Institutes of Science; 61st
Joint Annual Meeting of the National Institutes of Science/Beta Kappa
Chi/Brookhaven
Semester Program, Columbia, SC,
(March 2002).
McClung, Joseph M., W.J. Lee, R.W. Washington, C.M. Groschwitz, L. L.Lowe, and J.A. Carson. “Rho A Induction By Functional Overload and
Nandrolone Decanoate Administration
in Rat Skeletal Muscle”, Proceedings of the National Institutes of Science; 61st Joint Annual
Meeting of
the National Institutes of
Science/Beta Kappa Chi/Brookhaven Semester Program, Columbia, SC, (March 2002).
Eichelberger,
Eboni, L.L. Lowe. “Immunological
Characterization of Lactate Dehydrogenase Isoenzymes in Adult Male Rat Skeletal
Muscle
Exposed to Simulated Microgravity”, Abstract, 59th Joint
Annual Meeting of Beta Kappa Chi/National Institute of Science/Brookhaven
Semester Program, Columbia, SC (March 2002).
Harrington,
Michael, L.L. Lowe, “Molecular Cloning of Microgravity Responsive Genes”, Abstract, 59th Joint
Annual Meeting of Beta Kappa
Chi/National Institute
of Science/Brookhaven Semester Program, Columbia, SC (March 2002).
Clarke, Rawlins, IV and L. Lowe, “Amplification of
c-myc Generated cDNAs From Human and Mouse RNA Using Messenger RNA
Differential Display PCR”, Abstract, 57th Annual Joint Meeting,
Beta Kappa Chi and National Institute of Science-Brookhaven
Semester
Program, Nashville, Tenn., (April 2000).
Holmes, Patricia and L. Lowe, “Regression Modeling
of Heating and Cooling Efficiency Using a TI-83 Calculator-Based Lab”,
Abstract,
57th Annual Joint Meeting, Beta Kappa Chi and National Institute of
Science-Brookhaven Semester Program,
Nashville,
Tenn., (April 2000).
Garvin, L. and L. Lowe, “Amplification of cDNAs
Using Messenger RNA Differential Display PCR”, Abstract, 57th Annual Joint Meeting,
Beta
Kappa Chi and National Institute of Science-Brookhaven
Semester Program, Nashville, Tenn., (April 2000).
Clarke, Rawlins, IV and L. Lowe,
“Amplification of Human and Viral Genomic DNAs Using the Polymerase Chain Reaction”, Abstract,
56th Joint Annual Meeting of Beta Kappa Chi/National
Institute of Science/Brookhaven Semester Program, Oklahoma City,
Oklahoma (April 1999).
Counts, T.
and L.Lowe, “Effects of High Dose Amounts of Estrogen on Developing Chick
Embryos”, Abstract, 55th Joint Annual
Meeting of Beta Kappa
Chi/National Institute of Science/Brookhaven Semester Program, Philadelphia, PA
(April 1998).
Byrd, T. and
L. Lowe, “Isolation of Human-Specific Lactate Dehydrogenase-A cDNA
Clones”, Abstract, 55th
Joint Annual Meeting of
Beta Kappa Chi/National
Institute of Science/Brookhaven Semester
Program, Philadelphia, PA (April 1998).
Tarra Gibbs
and Larry L. Lowe, “Synthesis and Expression of Human Fetal Lactate
Dehydrogenase-B cDNA in Developing Mice” Abstract,
9th National Conference on
Undergraduate Research, Union College, Schenectady, NY 12308 (April 1995).
Larry L. Lowe and April Sanders, “Effects of Tail
Suspension and Recovery on Total Lactate Dehydrogenase Activity of the Soleus
Muscle”,
Abstract, Poster Presentation. NASA/University
Joint Venture Program Annual Meeting, Cocoa Beach, Florida, (July 1994).
Larry L. Lowe and Rosalind A. Grymes, “Effects of
Hindlimb Suspension and Recovery on Myogenic Helix/Loop/Helix Gene Expression
in Specialized Adult Muscle”, Abstract,
Poster Presentation, NASA/University Joint Venture Program Annual Meeting,
Galveston, Texas, (July/1993).
Larry L. Lowe and Rosalind A. Grymes, “Effects of
Hindlimb Suspension and Recovery on Myogenic Helix/Loop/Helix Gene Expression
in Specialized
Adult Muscle”, Abstract American
Society for Biochemists and Molecular Biology and Division of Biological
Chemistry. Abstract No. 149.
American Chemical Society. Joint Meeting,
Sanders, April and Larry L. Lowe, “Effects of Hindlimb Suspension and Recovery on Protein Gene Expression in Specialized Adult Muscle”,
Abstract, Annual Meeting of the South Carolina Academy of Science (1993).
Lowe, Larry L., Burke, B., Bose, N. and Johnson,
Joe, “Studies of Cap Analogues III. Inhibition of Eukaryotic Protein Synthesis
by
4-Thiouridine-5’-Monophosphate.” Proceedings of the National Black Chemist
and Chemical Engineers. 8th
Annual Meeting (1981)).
Lowe, Larry L. and Joe Johnson, Jr., “Inhibition
of Eukaryotic Protein Synthesis by Photoaffinity Binding Probe
4-Thiouridine-5’-Monophosphate
and
4-Thiouridine-5’-Diphosphate.” Abstract, 8th Annual Minority Biomedical Science Symposium, Atlanta,
GA (1979).
Lowe, Larry L., Isabella N. Finkelstein, Roosevelt
Thedford and Joe Johnson, Jr., “Use of
Luciferin-Luciferase (Firefly) Assay and Substrate
Analogues in Monitoring the Activity
of Polyadenylic Acid Polymerase:
ATP Dependent Riboadenylate Transferase”, Abstract,
7th Annual Minority
Biomedical Science Symposium, Atlanta, GA (1978).
Conference Proceedings (Unreviewed)
Stewart,
Kerry-Ann and L. Lowe, “The Effects of Microgravity Induced cDNA on Bacteria
Cell Transformation”, Abstract, Oral
Presentation, Annual
SC Independent Colleges and Universities Research Symposium, Greenville, SC (February 2003).
Research
Reports
Lowe, LL, “Aging
Skeletal Muscles Decreased Regenerative Capacity: Inflammation’s Critical Role”,
Benedict College/University of South Carolina,
Annual Progress Report,
NASA/EPSCoR/CRP, (August 2003).
Lowe, LL, “Minority
Access To Higher Education – Project M.A.T.H.E.”, Benedict College,
Quarterly and Annual Progress Reports, U.S. Department
of Commerce-TIIAP (March1999 –
December 2002).
Lowe, LL, “A
Collaborative Research Learning Environment”, Benedict College, Annual Progress Reports, NIH (MBRS) CRLE/LAN
Project, (June 1999 - June 2001).
Lowe, LL, “The
Isolation and Identification of Microgravity Responsive cDNAs”, Benedict
College, Annual Progress Reports, NASA/Faculty
Area Research Award, (June 1997 – June
2000).
Lowe, LL, “The
Effects of Microgravity on Gene Expression”, Benedict College, Annual
Progress Reports, South Carolina Space Grant Consortium,
(March 1995 to present).
Lowe, LL, “Benedict
College Summer Science Enrichment Program” Benedict College, Annual
Progress Report, U.S. Department of Energy,
Savannah River Site, (October 1994).
Lowe, LL, “Benedict
College Summer Science Enrichment Program” Benedict College, Annual
Progress Report, U.S. Department of Energy,
Savannah River Site, (October 1995).
Lowe, LL, “The
Effects of Simulated Microgravity on Myogenic Gene Expression”,
Benedict College, Annual Progress
Reports, NASA Joint
Venture Program, (October 1993 – October 1995).
Lowe, LL, “Suspension – Recovery Study”, NASA Ames Space Research Center, Moffett Field, CA, Technical Report, USRA NASA-JOVE,
(June – August 1992).
Other Scholarly Publications
(abstracts, invited reviews, discussions)
Southern University, Baton Rogue, Louisiana
Alliance for Developed Science and Math
Handbook (published, www.ls-lamb.org,
ISBN No. 0-9704609-1-0).
Minority
Participation (LAMP) MainSTey Project (1996-1997).
PRESENTATIONS
Lowe, L.L., “Undergraduate Research at Minority Institutions”, Quality Education
for Minorities (QEM) Network Meeting, Baltimore, MD (2001).
Lowe, L. L., “In Search of the Alien Gene – A Molecular Biology Approach”, Benedict College Brown Bag Speaker, Benedict College, Columbia, SC
(November 2000).
Lowe, L. L., “Project M.A.T.H.E. (Minority Access To Higher Education), - A Plan for Success” U.S. Department of Commerce, Washington, DC
(September 1999).
Lowe, L. L., “How to Prepare for a
Biomedical Research Career at NASA”, SC
Hartsville, SC (November
1994).
Lowe, L. L., “Teaching DNA Structure and Function on a Shoestring Budget”, 16: 244-247, Association of Biology Laboratory Educators
Conference, Emory University, Atlanta, GA (June 1994).
Lowe, L.L. and Rosalind Grymes, “Effects of Hindlimb Suspension and Recovery on Myogenic
Helix/Loop/Helix (HLH) Gene Expression
in Adult Muscle”, Annual Meeting of the South Carolina Academy of Science (1993).
HONORS AND AWARDS
Member, Beta Kappa Chi National Scientific Honor
Society (1978 to Present)
Member, Outstanding Young Men of America (1982)
Member, Phi Eta
Sigma National Scientific Honor Society (1985)
NASA/JOVE, NASA Research Award in Excellence
(1998)
Benedict College, Dedicated Service Appreciation
Award, Benedict College (2001)
Governor’s School of Science and Mathematics,
Summer Science Program, Dedicated Service Appreciation Award (2002)
Strathmore’s Who’s Who (2006 – 2007 Edition)
William C. Foster Visiting Scholar, United States Department of State, Science Advisor, Office of Defense Trade Controls Policy, Bureau of Political-Military
Affairs, Washington, D.C. (January 2008 – January 2009).
SPONSORED RESEARCH
“The Effects of Microgravity on Gene Expression”,
South Carolina Space Grant Consortium, Campus Director, $18,500 ($18,500) (1995
to present).
“Aging
Skeletal Muscles Decreased Regenerative Capacity: Inflammation’s Critical
Role”, NASA/EPSCoR/CRP, Principal Investigator,
$30,000 ($10,000), (2003 - 2004).
“Aging Skeletal Muscles Decreased Regenerative
Capacity: Inflammation’s Critical Role”, NASA/EPSCoR/CRP, Principal
Investigator,
$93,146 ($58,924), (2002 - 2003).
“Minority Access To Higher Education – Project M.A.T.H.E.”,
U.S. Department of Commerce-TIIAP, Project Director, $1,112,695
($1,112,695), (1999 – 2002).
“A Collaborative Research Learning Environment”,
NIH (MBRS) CRLE/LAN Project, Project
Director, $ (June 1999 - June 2001).
“The Isolation and Identification of Microgravity
Responsive cDNAs”, NASA/Faculty Area Research Award, Principal Investigator,
$298,386 ($298,386) (1997 – 2000).
“The
Effects of Simulated Microgravity on Myogenic Gene Expression”, NASA Joint
Venture Program, Marshall Space Flight Center,
Huntsville, Alabama, Principal
Investigator, $110,000 ($110,000) (1993
– 1995).
“Benedict College Summer Science Enrichment
Program” U.S. Department of Energy, Savannah River Site, Co-Principal
Investigator,
$689,000 ($689,000) (1994-1995).
“Benedict College Summer Science Enrichment
Program” U.S. Department of Energy, Savannah River Site, Principal
Investigator,
$689,000 ($689,000) (1995-1996).
“Skeletal Muscle Protein Gene Expression”,
NIH/MARC, Co-Principal Investigator, $ 5,000 (1992-1996)
“NASA Undergraduate Research Scholar’s Program”,
NASA Joint Venture Program, Marshall Space Flight Center, Huntsville, Alabama,
Principal Investigator, $30,000
(1992-1995).
OTHER
SPONSORED ACTIVITY
Title III Chemistry Grant, US Department of Education, $104,978, (2002 to present)
GRADUATE
STUDENT ADVISING (5 Total to present)
Doctoral
Graduates (Trained in
biomedical and molecular biology research)
Hunter,
E.E., “Biochemical Characterization of Eukaryotic Ribosomal Proteins” (Photoaffinity
Labeling and In Vitro Translation Assays).
(1979 – 1981).
Department of Chemistry, Atlanta,
GA,
University of South Carolina,
Department of Exercise Science. (2003 to
2008).
Masters Graduate (Trained in
biomedical and molecular biology research)
Hodges, Ruth, “Isolation of Eukaryotic Large and Small Ribosomal
Particles Using Ultra Centrifugation Techniques”. (1979 – 1981).
Department of
Chemistry, Atlanta University, Atlanta, GA.
Brannon,
Cheryl, T., “Simulated Microgravity Suspension and Recovery – Computer Graphics
of Selected Data Report”. (1994).
Department of Biological and
Physical Sciences, Benedict College, Columbia, SC.
Current Graduating Advising
( None)
Post-Doctoral Research
Advisees: (None – to – date)
TEACHING:
Courses
Taught (Beginning Spring 1991)
Bio 248, Genetics. 1991 - present
Chem 242, Principles of Chemistry II. 1991 –
1994
Chem 241, Principles of Chemistry I. 1991 – 1994
Chem 343, Analytical Chemistry. 1991 – 1994
Chem 448, Biochemistry. 1993 - 1995
Sci 335, Biomedical Research Techniques. 1991 – 1996
Bio 448, Cell and Molecular Biology. 1992 to present
Bio 140, General Biology (non-majors). 1991 – 1995
Bio 337, Nutrition. 1995
Bio 444, Plant Physiology. 1994
Bio 330, Evolution. 1996
Bio 344 Vertebrate Embryology. 1994, 1996
Bio 147, Principles of Biology I. 2000 to present
Bio 148, Principles of Biology II. 2000 to present
Bio 233, Human Anatomy and Physiology I and II. 2001 to present
New Course Deve1opment
Sci 335, Biomedical Research Techniques
Bio 448, Cell and Molecular Biology
Bio 448H, Cell and Molecular Biology (Honors)
UNIVERSITY AND PUBLIC SERVICE:
“Genetics,”
Visiting Lecturer and Instructor, Governor’s
“59th Joint Annual Meeting of Beta Kappa Chi/National Institutes of Science/Brookhaven Semester Program”,
Conference Chair, Columbia, SC (March 2002).
Committees
Department: Member, Faculty Recruitment
Committee (1992 –1994)
Department: Member-At-Large, Faculty
Recruitment Committee (2002 - present)
College: Member, Dean for
College: Athletics Committee (1995 – 1998)
College: Honorary Degree Committee
(1999-2001)
College: Member, Student Judiciary Committee
(2002 - present).
College:
Member, Biohazards and Radiation Safety Committee (2000- 2002)
College: Member-At-Large, Biohazards and
Radiation Safety Committee (2003 - present)
College: Academic Affairs Expanded Council
(2002 - )
College:
Member, Minority Access to Research Careers (MARC) Honors Undergraduate Program
Steering Committee (2002 – 2003)
College:
Member, Research Infrastructure at Minority Institutions (RIMI) Advisory
Committee (2002 - present)
School: Humanities, Arts and Social Sciences
Faculty Tenure and Promotion Committee (2002- present)
School:
School:
General Education Requirement Advisory Committee (2007)
University: Member, Ph.D. Thesis Committee, Mr. Tyrone
Washington, School of Public Health, Department of Exercise Science,
University of South Carolina, Columbia (2008)
Other Service
Moderator and Lead Coordinator, U.S.
Department of State, US Government Export Controls Conference For Academic
Researchers, Fair Lakes, VA (2008)
Director, Benedict College/Friendship Baptist
Church Science Academy (1995 - present)
Chapter Sponsor, Alpha Theta
Chapter (
Project Manager, USRA NASA-JOVE Microgravity Suspension and Recovery Study, NASA Ames Space Research Center,
Moffett Field, CA (June – August 1992).
Upon Request