DR.LARRY LENARD LOWE - BIOGRAPHICAL SKETCH

401 chantilly Circle

Seneca, SC 29678

(864) 882-5188

EDUCATION

 

Tougaloo College, Tougaloo, MS - B.S. Biology, 1972

University of Michigan, Ann Arbor, MI - M.S. - Zoology, 1975

Atlanta University, Atlanta, GA - Ph.D. Biology, 1980

Harvard University, Cambridge, MA - Summers School and Undergraduate Research Scholar - Biology and

chemistry, 1969, 1970, and 1971

University of California, Santa Cruz Exchange Student - Biology, 1971

University of Southern Miss. Hattiesburg, MS, Summer School Student - Medical Genetics, 1972

 

EMPLOYMENT AND RELATED ACTIVITIES

 

Chair (2002 – Present) and Professor (1991 to Present), Biology, Chemistry and Environmental Health Science Department

NASA Research Fellow, NASA Ames Space flight Center, Moffett Field, CA

Associate Professor, Biology, Benedict College, 1991 - 1999

Distinguished Faculty Member of the Year, 1999 - 2000

Governor’s Distinguished Professor Award, 2001

National Chairperson, 59th Joint Annual Meeting of the National Institute of Science/Beta

Kappa Chi/Brookhaven Semester Program.  Adam’s Mark Hotel, Benedict College Host Institution, 2002

PI and Senior Scientist (Mentor), NASA/EPSCoR/CRP Research Project, Benedict College/University of

South Carolina, Columbia Campus, Department of Exercise Science

PI, Benedict College/U.S. Department of Commerce-TIIAP M.A.T.H.E. Project, 1999 - 2002

PI, NIH (MBRS) CRLE/LAN Project, 1999 - 2001

PI, NASA/FAR Microgravity Research (molecular biology), 1997 - 2000

Director, Benedict College/Friendship Baptist Church Science Academy, 1995 - Present

Campus Director, South Carolina Space Grant Consortium, 1995 - present

Co-PI, MARC Research Grant (Skeletal Muscle Protein Gene Expression)

PI, Governor's School of Science and Mathematics (GSSM) Summer Science Program (SSP) Genetics

Follow-Up Program

PI and Mentor to several funded undergraduate and graduate research awards

Sponsor, Alpha Theta Chapter (Benedict College) Beta Kappa Chi

Science Consultant, Benedict College Child Development Center

Associate Professor of Biology, Alcorn State University (1988-89)

Visiting Research Assistant Professor of Biology, University of Virginia, Charlottesville, VA

 (1989-1991)

Consultant (Science Technology), Louisiana Alliance for Minority Participation (LAMP) MainSTey

Project, 1996-1997.

Assistant Professor of Biology and Research Associate (Biochemistry), Atlanta University Center

And Morehouse School of Medicine (1986-88)

NIH Postdoctoral Fellow, Department of Microbiology and Immunology, Emory University School of

Medicine, Atlanta, GA (1982-85)

Assistant Professor, Department of Biology, Atlanta University (1980-82)

Instructor, Department of Biology, Clark College (1977-80)

Chairman and Instructor, Department of Natural Sciences; Director MISIP Grant, Morristown

College, Morristown, TN (1976)

Hemodialysis Technician II, University Hospital, Hemodialysis Unit, Ann Arbor, MI (1973-75)

 

HONORS, AWARDS RESEARCH

 

NASA Research Fellow

Dedicated Service Appreciation Award, Benedict College, 1991-2001

Distinguished Faculty Member of the Year, 1999 - 2000

Governor’s Distinguished Professor Award, 2001

Nominee, 2001 Governor’s Professor of the Year

U.S. Department of Commerce TIIAP Project, 1999-2002 (Funded)

NIH/MBRS Supplemental Grant, 1999-2001 (Funded)

NASA/FAR Research Grant Award, 1997-2000 (Funded)

South Carolina Space Grant, 1995-2000 (Funded)

NASA Research Award in Excellence, 1998

NASA/JOint VEnture Research Grant, Microgravity (Skeletal Muscle Atrophy), 1992-1995 (Funded)

NIH Minority Faculty-Student Partnership Traineeships in Biotechnology Award, summer 1995

NIH Faculty Research Supplemental Grant, Molecular Biology (Skeletal Myogenesis), University of

Virginia, Charlottesville, 1989-1991 (Funded)

(Funded)

Member, American Heart Association, Mississippi Affiliate, Research Advisory Policy Committee

1988-89

NIH Postdoctoral Fellow, Emory University School of Medicine, Mol. Virology, 1982-85 (Funded)

Beta Kappa Chi National Scientific Honor Society

Phi Eta Sigma National Scientific Honor Society

Sigma Xi, The Scientific Research Society

Outstanding Young Men of America

Member, South Carolina Jr., and South Carolina Academy of Sciences

 

 

SELECTED PUBLICATIONS

 

RhoA Expression During Recovery From Skeletal Muscle Disuse.  J.M. McClung, R.W. Thompson, *Larry L. Lowe, and J.A. Carson.  Department of Exercise Science, Integrative Muscle Biology Laboratory, School of Public Health, University of South Carolina, 29208; and *Department of Biology and Physical Sciences, Benedict College, Columbia, SC 29290. Journal of Applied Physiology, 96:000-000, 2004.

 

RhoA Induction by Functional Overload and Nandrolone Decanoate Administration in Rat Skeletal Muscle.  Joseph M. McClung, Won J. Lee, Raymond W. Thompson, Larry L. Lowe* and James A. Carson.  Integrative Muscle Biology Laboratory, Department of Exercise Science, Norman J. Arnold School of Public Health, University of South Carolina, Columbia, SC 29208.  *Department of Biology and Physical Sciences, Benedict College, Columbia, SC 29204. European Journal of Physiology, 447:345-355, 2003.

 

Lactate Dehydrogenase Activity in Functionally Overloaded Rat Plantaris Muscle.  Washington, T. A., J.M. McClung, *L.L. Lowe, PhD, and J.A. Carson, PhD. University of South Carolina, Department of Exercise Science and *Benedict College, Department of Biological and Physical Sciences, Columbia, SC. Accepted, Southeastern American College of Sports Medicine National Meeting, St. Louis, MO, 2002.

 

Decreased Lactate Dehydrogenase Activity at the Onset of Functional Overload in Rat Plantaris Muscle. Washington, T.A., J.M. McClung, *L.L. Lowe, PhD, and J.A. Carson, PhD. University of South Carolina, Department of Exercise Science and *Benedict College, Department of Biological and Physical Sciences, Columbia, SC. Accepted, Southeastern American College of Sports Medicine National Meeting, St. Louis, MO, 2002.

 

 

Amplification of c-myc Generated cDNAs From Human and mouse RNA Using Messenger RNA Differential Display PCR.  Rawlins Clarke, IV and L. Lowe, Department of Biological and Physical Science, Benedict College, Columbia, SC 29204.  57th Annual Joint Meeting, Beta Kappa Chi and National Institute of Science-Brookhaven National Laboratory, Nashville, Tenn., April 2000.

 

 

Regression Modeling of Heating and Cooling Efficiency Using a Ti-83 Calculator-Based Lab.  Patricia Holmes and L. Lowe, Department of Biological and Physical Science, Benedict College, Columbia, SC 29204.  57th Annual Joint Meeting, Beta Kappa Chi and National Institute of Science-Brookhaven National Laboratory, Nashville, Tenn., April 2000.

 

Synthesis and Expression of Human Fetal Lactate Dehydrogenase-B cDNA in Developing Mice.  *Terra Gibbs and Larry L. Lowe, Department of Biological and Physical Sciences, Benedict College, Columbia, SC 29204.  Abstract, 9th National Conference on Undergraduate Research, April 20-22, 1995, Union College, Schenectady, NY 12308.

 

Effects of Tail Suspension and Recovery on Total Lactate Dehydrogenase Activity of the Soleus Muscle. Larry L. Lowe and *April Sanders, Benedict College, Columbia, SC 29204.  Abstract, Poster Presentation.NASA/University Joint Venture Program Annual Meeting, Cocoa Beach, Florida, July 1994.

 

Effects of Hindlimb Suspension and Recovery on Myogenic Helix/Loop/Helix Gene Expression in Specialized Adult Muscle.  Larry L. Lowe and Rosalind A. Grymes.  Benedict College, Columbia, SC 29204 and Life Science Division, NASA-Ames Research Center, Moffett Field, CA 94035.  Abstract American Society for Biochemists and Molecular Biology and Division of Biological Chemistry.  American Chemical Society.  Joint Meeting, San Diego, CA.  May 30 - June 3, 1993.  Abstract No. 149.

 

Guang jer Wu, Shu-Ying Lu, Larry L. Lowe and Joseph M. Kinkade, Jr. 1985. Identification of Lactate Dehydrogenase-M Polypeptide Translated in vitro form Human and Mouse Tumor Cell Poly (A)-Containing mRNA.  Emory University School of Medicine, Atlanta, Ga. 30330. International Journal of Biochemistry.  Vol. 17:133-137.

 

Effects of Hindlimb Suspension and Recovery on Myogenic Helix/Loop/Helix Gene Expression in Specialized Adult Muscle.  Lowe, Larry L. (Benedict College) and Rosalind A. Grymes (Ames Research Center).  Abstract, Poster Presentation.  NASA/University Joint Venture Program Annual Meeting, Galveston, Texas, July 10, 1993.

 

Lowe, Larry L., Burkes, B., Bose, N. and Johnson, Joe.  1981.  Studies of Cap Analogues III.  Inhibition of Eukaryotic Protein Synthesis by 4-Thiouridine-5'-Monophosphate and 4-Thiouridine-5'-Diphosphate.  Atlanta University Center, Inc., Atlanta, Ga. 30314.  Proceedings of the National Black Chemists and Chemical Engineers, 8th Annual Meeting.

 

Larry L. Lowe and Joe Johnson, Jr.  Inhibition of Eukaryotic Protein Synthesis by Photoaffinity Binding Probe 4-Thiouridine-5'-Monophosphate and 4-Thiouridine-5'-Diphosphate.  Department of Biology, Atlanta University Center, Inc., Atlanta, Ga. 30314.  8th Minority Biomedical Science Symposium, Atlanta, Ga. 1979.

 

Larry L. Lowe, Isabella N. Finkelstein, Roosevelt Thedford and Joe Johnson, Jr.  Use of Luciferin-Luciferase (Firefly) Assay and Substrate Analogues in Monitoring the Activity of Polyadenylic Acid Polymerase: ATP Dependent Riboadenylate Transferase.  Atlanta University Center, Inc., Atlanta, Ga. 30314.  Abstracts 7th Minority Biomedical Science Symposium.  Atlanta, Ga. 1978.

 

Larry L. Lowe.  In vitro Metabolism of 11-hydroxy-delta-9-THC by the Rat Liver Microsomal Enzyme Cytochrome P450.  Department of Zoology, University of Michigan, Ann Arbor, MI.   1975.  Masters Thesis.

 

RESEARCH INTERESTS

Differential Gene Expression and Regulation. This Research Focuses Primarily on the Effects of Space Flight or Simulated Microgravity on Protein Gene Expression in Adult Fiber Type-Specific Skeletal Muscles.